A model of the T-junction of a C-fiber sensory neuron (Sundt et al. 2015)

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Contributor:NIJC Administrator (nijcadmin)  |  Created Date: Dec 20, 2017 20:13:26  |  Visits:732  |  Runs:8
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ID 656
Title A model of the T-junction of a C-fiber sensory neuron (Sundt et al. 2015)
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Description Two versions of the model of an un-myelinated, C-fiber sensory neuron are simulated by NEURON.

The two versions generate Figures 5d and 8c in the reference paper. Figure5d varies M-channel density and illustrates where the reflecting spike generated. Figure8c illustrates the effect of the Na/K pump on membrane potential and spike failure at the T-junction.

Reference
Sundt D, Gamper N, and Jaffe DB. Spike propagation through the dorsal
root ganglia in an unmyelinated sensory neuron: a modeling study. J
Neurophysiol. 2015 Dec 1;114(6):3140-53
Last Modified Date Jan 4, 2018 17:58:17
Created Date Dec 20, 2017 20:13:26
Contributor NIJC Administrator (nijcadmin)
Item Type Online Simulation
Change Log(History)
Jan 4, 2018 Modified; Index.
Jan 4, 2018 Modified; Index.
Dec 21, 2017 Modified; Description.
Dec 21, 2017 Modified; Index.
Dec 21, 2017 Modified; Preview.
Model Contents URL https://senselab.med.yale.edu/ModelDB/showModel.cshtml?model=187473
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Model Site Name ModelDB
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